Detail introduction:Exenatide/Exenatide acetate/141732-76-5
| English name | Exenatide |
| CAS NO | 141732-76-5 |
| Peptide sequence | His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Molecular formula | C186H286N50O62S |
| Molecular weight | 4244.61 |
| storage temperature | 2-8℃ |
| purity | ≥98% |
| Package | 1mg;5mg;10mg;50mg;100mg,1g or according to customer’s detail requirement. |
| Product English synonyms | Exenatide acetate; Extendin-4 |
What is Exenatide?
Exenatide is a synthetic GLP-1 (glucagon-like peptide) analogue, composed of 39 amino acids. It is an incretin mimetic drug that can mimic the effects of glucose-dependent insulin secretion enhancement and other antihyperglycemic effects of incretin.
What is the mechanism of action of Exenatide acetate?
The amino acid sequence of It partially overlaps with human GLP-1. Exenatide has been shown to bind to and activate the known human GLP-1 receptor in vitro. This means that glucose-dependent insulin synthesis and insulin secretion by pancreatic β cells in the body is increased by including cAMP (cyclic adenosine monophosphate) or other intracellular signaling mechanisms.
Mechanism of Exenatide’s action
It is a human glucagon-like peptide-1(GLP-1) receptor agonistLabel. By activating this receptor, insulin secretion is increased and glucagon secretion is decreased in a glucose-dependent mannerLabel. It also slows gastric emptying and decreases food intakeLabel. These effects work synergistically to improve glycemic control by reducing the likelihood of hyper and hypoglycemiaLabel.
How to buy Extendin-4 in the U. S.
Peptide supplier Remetide specializes in the production and sales of peptides in the USA, as well as Professional Drug peptide R&D. Feel free to contact us if you have any questions or inquiries about Extendin-4 Peptide.